Treatment for Knee Pain Without Surgery: What Really Works?

If you’re looking for treatment for knee pain without surgery, you’re not alone. Many people living with osteoarthritis want real relief—without jumping straight to joint replacement. The good news? There are proven non-surgical options that work, including a new procedure called Genicular Artery Embolization (GAE).

man running outdoors with knee pain before gae

1. Start with the Basics: Conservative Care

When it comes to treatment for knee pain without surgery, conservative care is often the first step.

  • Physical therapy to strengthen supporting muscles

  • Weight management to reduce pressure on joints

  • Anti-inflammatory medications (NSAIDs)

  • Assistive devices like knee braces or orthotics

These approaches can help in early stages, but they often lose effectiveness as osteoarthritis progresses.

For more on conservative osteoarthritis treatment options, visit the Arthritis Foundation.

2. Injections: Short-Term Relief

When over-the-counter remedies aren’t enough, some patients try:

  • Corticosteroid injections – reduce inflammation but wear off in weeks to months

  • Viscosupplementation (hyaluronic acid) – adds lubrication but doesn’t reverse damage

  • Platelet-Rich Plasma (PRP) – still being studied, varies by provider

While these may help with symptoms, their effects are temporary—and they don’t stop the underlying joint degeneration.

3. Genicular Artery Embolization (GAE): A Proven Treatment for Knee Pain Without Surgery

One of the most promising non-surgical options is Genicular Artery Embolization (GAE)—a minimally invasive outpatient procedure that targets the source of inflammation in osteoarthritic knees.

How It Works:

During GAE, a specialist uses imaging to guide a tiny catheter into the arteries that supply blood to the inflamed joint lining. Microscopic particles are injected to block this abnormal blood flow, reducing inflammation and pain.

Why It’s Gaining Popularity:

  • No hospital stay

  • Quick recovery (most return to light activity in a day or two)

  • Proven to reduce knee pain in patients with moderate osteoarthritis

  • Ideal for patients who aren’t ready for or want to delay joint replacement

Learn more about how Genicular Artery Embolization works.

4. When Is It Time to Consider GAE?

You might be a candidate if you:

  • Have been diagnosed with knee osteoarthritis

  • Still experience pain despite injections or physical therapy

  • Want to avoid or delay knee surgery

  • Prefer a less invasive option with a shorter recovery

GAE is especially helpful for patients in the “gray zone”—when conservative treatment no longer works, but surgery feels too aggressive.

5. The Bottom Line

You don’t have to live with chronic knee pain—or rush into surgery. Thanks to advances like Genicular Artery Embolization, patients now have real, non-surgical solutions that provide relief and restore mobility.

If you’re exploring treatment for knee pain without surgery, our team at Preferred Vascular Group in Cleveland and Atlanta can help.

Schedule a consultation today to find out if GAE is right for you.